Stem Cell Therapy

Stem Cell Therapy is the use of healthy stem cells to stimulat the activity of the cells within the body. In addition, the stem cell therapy also helps to promote the repair response of diseased, dysfunctional or injured tissues by regenerating new cells and replacing the damaged cells in order to treat or prevent the disease. Stem cells therapy is also used in the anti-aging medicine to help to restore the health and revitalize the youth, slow down the aging process.

Benefits of Stem Cells in anti-aging and treating diseases caused by cells and organ degeneration.

  1. Enhance the growth of cells and the cell regeneration;
  2. Maintain the functions of the cells , and replace specialized cells that are damaged or lost;
  3. Provide necessary substances in the process of repairing the damaged cells, which are involved in reducing inflammation and stimulating cell renewal.

What kind of diseases can stem cells treat?

Currently, stem cells used in medical practice can be divided into two main categories: Hematopoietic Stem Cells and Mesenchymal Stem Cells.

Hematopoietic Stem Cells

Hematopoietic stem cells are mainly produced in the bone marrow, and can be generated into the components of blood, such as white blood cells, red blood cells and platelets. In Thailand, the hematopoietic stem cells are in the clinical practices of treating leukemia and lymphomas cancer.

According to the origin of donor, the hematopoietic stem cells can be classified into 2 types:

  1. Autologous Stem Cell is the stem cell used the patient’s own blood stem cells for the transplant.
  2. Allogenic Stem Cell is the stem cell from a donor’s blood. These types of stem cells can come from the patient’s brothers or sisters in the family as well as anyone who is interested in donating.

There are 3 types of hematopoietic stem cells commonly used in general medical practice:

  1. The placental umbilical cord contains a large amount of blood stem cells. After the baby was born, the surgeon will cut the umbilical cord attached to the placenta apart and collect the blood from the umbilical cord. In this way, it will not affect the baby;
  2. The bone marrow is also a good source of stem cells. It contains a large quantity of high-quality blood stem cells;
  3. Human’s blood. Normally, in our body, there is a relatively small amount of blood stem cells. When our immune system is stimulated, the white blood cells will increase the blood stem cells in the bloodstream.

Mesenchymal Stem Cells 

Mesenchymal stem cells (MSCs) are adult stem cells isolated from different sources that can differentiate into other types of cells. In humans, these sources include; bone marrow, fat, umbilical cord or amniotic fluid, and can be generated into bones, cartilage and fat.

At present, mesenchyme stem cells (MSC) are widely used in the medical practice, for example, the use of mesenchyme stem cells in the treatment of neurological diseases, bone marrow diseases, eye diseases, diabetes, bone disease and other autoimmune diseases(ref 2). Please see the summary and references in the Table 2.

The new studies and research of stem cells also discovered that the mesenchymal stem cells (MSC) have been used to treat knee and joint pain in Thailand.

In the field of anti-aging medicine, this type of mesenchymal stem cells is used for the skin rejuvenation. By injecting the stem cells into the layer of the skin to stimulate the collagen production and remove the wrinkles.

Stem cells therapy in anti-aging helps to enhance the mechanism and regenerative ability of the cells, as well as increase the the production of collagen and elastin from the fibroblasts. What’s more, it improves the blood circulation in the face. (ref 3)

Mesenchyme stem cells can be collected from many sources. At Novavida Integrative Medical Center, we provide 3 types of mesenchyme stem cells:

  1. Wharton’s Jelly derived MSC from the umbilical cord.  
  2. Placenta derived MSC from the placenta.
  3. Amnion membrane-derived MSC from the placental membrane.

Novavida’s experienced doctors will best customize the treatment plans for each patient depending on the needs of the patient.

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The stem cells that are used in the treatment include:

1. Stem cells from the patient’s own body (Autologous MSCs)

The stem cells will be collected from the patient’s own blood. This type of stem cells can generate into various types of cells, such as muscle cells, fat cells to produce collagen, cartilage cells to support bone integrity and so on. Novavida collects the stem cells from the patient’s own blood and have them cultivated in a sterile laboratory (Cleanroom Class100) free from fungal, bacterias and viruses, ensuring the highest safety level of the stem cells, avoiding the allergy or incompatibility.

2. Stem cells from others (Allogeneic MSCs)

Allogeneic MSCs is the stem cell not from from the patient’s own. Before this type of stem cell is injected to the patient’s body for the stem cell therapy, it must be strictly screened and checked from infectious diseases for both the original stem cells and the cultivated stem cells. Normally such stan cells are collected from the placenta, umbilical cord and the dental pulp, etc.

3. Stem cells from animals (Animal Fetal Stem Cells)

Such stem cells are usually collected from the animals, such as sheep, rabbits by obtaining the stem cells from the organs of the fetus, then cultivate the stem cells in the laboratory. Before this type of stem cell is injected to the patient’s body, it must be strictly screened and checked from infectious diseases.

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What types of stem cells do Novavida choose?

“Novavida only provides the stem cells derived from the patient’s own blood for the treatment, and uses such stem cells to be cultivated in the lab. This type of stem cell will cause no side effects or stimulation of the antibody.”

Process of stem cells therapy in the treatment of disease

Before the treatment, there will be an evaluation and pre-treatment testing on the health of the patient, the doctor will conduct a customized treatment plan for the patient;

  • A sample of 10-15 ml blood will be taken from the patient for mesenchymal stem cells (MSCs) isolation and screening;
  • Cultivate the stem cells in Novavida’s world-class sterile laboratory (Cleanroom Class100).
  • By using the culture medium which has been researched and under development for more than 20 years from Italy, the lab can cultivate at least 80-100 million stem cells within 30 days;
  • Strictly screen and check the purity and quality of the stem cells to prevent the fungal and bacterial infection before the transplant treatment;
  • The stem cells will be administered intravenously to the patient 4 – 6 times per month. (For the best result, the doctor may recommend 4 consecutive doses of autologous MSCs for a 4-month period);

Note:

  • For those who want to treat the diseases caused by the degeneration of cells and organs;
  • The doctor may recommend 6 consecutive doses of autologous MSCs for a 6-month period.
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Advantages of Stem cell therapy of Autologous MSCs

Autologous stem cells consist of

  • Hematopoietic Stem Cell; HSCs
    These hematopoietic stem cells will generate into the components of the blood including red blood cells, white blood cells and platelets. The HSCs therapy has been approved by the medical council to be used in the treatment of hematological diseases.
  • Mesenchymal Stem Cell ; MSCs
    These mesenchymal stem cells can generate into the components of various tissues in the human body, such as bones, cartilage, tendons, muscles and fat, etc. The research and studies recently also showed that the mesenchymal stem cells can help relieve the muscle and joint pain, treat the bone diseases, high blood pressure and liver diseases.

What to pay attention to before and after the treatment?

Cautions before receiving the stem cell therapy

  1. Avoid spicy food at least 2 weeks before the stem cell therapy;
  2. Drink water regularly (2 liters/day);
  3. Avoid drinking alcohol 2 weeks before the stem cell therapy;
  4. Exercise regularly;

Cautions after receiving the stem cell therapy

  1. Avoid spicy food at least 2 weeks after the stem cell therapy;
  2. Drink water regularly (2 liters / day);
  3. งดการดื่มแอลกอฮอล์ 2 สัปดาห์หลังทำเซลล์บำบัAvoid drinking alcohol at least 2 weeks after the stem cell therapy;
  4. Avoid strenuous exercise;
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Why choose the stem cell therapy at Novavida?

Novavida Integrative Medical Center is a holistic health care center providing the world-leading technology from Italy facial rejuvenation stem cells treatment, with Professor Ivan Torrente, the physician specializing in stem cell therapy and gene therapy from University of Milan, Italy as the consultant physician.

Novavida never stops exploring in bringing the world-class gene and cells innovations to the health care, and put them into the pratical uses. Novavida also has its own laboratory for stem cell cultivation with the world’s highest safety level and international standard.

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